cellXpress pro 2.4.0 (10 June 2024)

• Added WSI tissue viewer for visualizing whole slides and selecting ROIs for processing.
• Adding custom markerset display for WSI tissue viewer.
• Added support for COMET, CODEX, and OME-TIFF images.
• Added direct ROI processing for WSI images.
• Improved image metadata extraction.
• Implemented a data container framework and "Slide" is now the default container type for new project.
• [Known issue] On MacOS, the WSI tissue viewer may crash during zoom in but the image processing is stable and accurate. Tentative remedy is to avoid zooming in the image. Windows and Linux are not affected.

cellXpress pro 2.3.10 (18 July 2023)

• [Common] This is a bugfix release for MacOS only that fixes the crashing problem due to missing external libraries.
• [Common] The minimum version of MacOS has been increased to 13.

cellXpress pro 2.3.9 (27 April 2023)

• [cXViewer] Fixed a bug in displaying feature values while browsing an image
• [Common] Fixed a bug in exporting single-cell data and loading external subpopulation definitions for non-merging-markerset projects
• [Common] Updated external libraries
• [Common] GPU acceleration required NVIDIA driver ≥525.60.13 (Linux) or ≥527.41 (Windows)
• This will be the last version for macOS (x64)

cellXpress pro 2.3.8 (9 November 2022)

• First public production release of cellXpress 2.
• Added multi-marker-set merging function
• Added CellShape AI (CSAI) segmentation
• Added CUDA support for CSAI acceleration
• Added subpopulation detection
• Added subpopulation visualization
• Added external clustering visualization function
• Added autofluorescence (SNR) measurement
• Added population feature extraction
• Added support of additional containers (slides and tissue microarrays)
• Added online reference project download function
• Added ROI annotation function for tissue images
• Added OME-TIFF and QTIFF image support
• Added auto detection and switching to CPU-optimized code
• Improved memory allocation efficiency and image processing speed
• Ported to macOS

cellXpress pro 1.4.2 (8 March 2017)

• Fixed a bug in loading images with no cell.

cellXpress pro 1.4.1 (13 Feb 2017)

• Fixed a bug in loading images with non-zero-based channel indexes.

cellXpress pro 1.4 (2 Feb 2017)

• [Feature Extraction] Added chromosomal-region detection and features
• [PlateViewer] Display range has been changed from min-max to 5-95 percentiles
• [cXViewer] Added SNR calculation for autofluorescence detection
• [Profiling] Added plate view format for exporting feature values
• [Profiling] Added directory removal for clearing existing segmentation or feature data files
• [Common] Added OpenCL detection code
• [Common] Optimized the chunk size for column reading (more than doubles the feature loading speed)
• [Common] Fixed a bug in the cell-region percentile measurement
• [Common] Fixed several other minor bugs
• [Common] Updated to OpenCV 3.2.0 and wxWidgets 3.1.0

cellXpress pro 1.3 (5 Oct 2015)

• Updated to OpenCV 2.9.10 and wxWidgets 3.0.2.
• Optimized for 64-bit CPUs with AVX/AVX2 support.
• Added desktop link file for Linux.
• Minor bugs fixed.

cellXpress pro 1.2 (30 May 2014)

• Updated to OpenCV 2.9.4 and wxWidgets 3.0.
• New function to add multiple plates under a folder.
• More robust procedures to handle and report corrupted images.
• Can resume unfinished segmentation and feature extraction jobs. Useful for large-scale processings.

cellXpress pro 1.1 (20 May 2013)

• [Segmentation] Added DIC watershed-based cell segmentation algorithm.
• [Feature extraction] Added Haralick texture, Hu moment, and local structure features.
• [Tools] Added DIC image alignment tool.

cellXpress pro 1.0 (10 Jan 2013)

• First public production release.
• Modules: cellXplorer, cellViewer, and cXlibrary.
• Feature extraction: morphology, intensity, intensity ratio, and pixel-level correlation features.
• Profiling: SVM-based d-profiles.